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Quadruple marker

Parameters1 tested
SampleBlood
FastingNot required
Report in24-48 hrs

How to prepare

No fasting needed

You can eat and drink normally before the test.

Good to know

No special preparation needed.

Medicines

Tell our phlebotomist about any medicines you take. Don't stop them without asking your doctor.

Comfortable clothes

Wear a loose sleeve so the sample can be taken easily from your arm.

How it works

Book onlinePick a time slot
Home visitSealed, sterile kit
Lab testingBarcode tracked
ReportIn 24-48 hrs

About this test

The quadruple marker is a second-trimester screening test done between 15 and 20 weeks. It measures AFP, hCG, unconjugated estriol and inhibin A to estimate the risk of Down syndrome, Edwards syndrome and neural tube defects.

Why is this test done?

  • Screen for chromosomal conditions when first-trimester screening was missed
  • Screen for neural tube defects like spina bifida

Symptoms — when should you get tested?

  • Routine screening at 15–20 weeks
  • Missed dual marker test
  • Higher maternal age

Normal range

Risk Screen negative (low risk)

Reference ranges differ slightly between labs, methods, age and sex. Always discuss your report with your doctor.

If your result is high

A screen-positive result means a higher chance, and further tests such as a detailed scan, NIPT or amniocentesis may be advised.

Common reasons
  • Higher chance of Down syndrome
  • Higher chance of trisomy 18
  • Neural tube defects (high AFP)

How is the test done?

  1. 1
    Book online

    Choose your slot for home collection or a visit to our centre.

  2. 2
    Blood sample taken

    A trained phlebotomist takes a small blood sample from a vein in your arm with a sealed, single-use needle. It takes about 2 minutes.

  3. 3
    Tested in our lab

    Your barcoded sample is tested on automated machines with strict quality checks.

  4. 4
    Report on WhatsApp

    A pathologist checks the result and the report reaches you on WhatsApp and email.

Frequently asked questions

The risk calculation depends on exact pregnancy weeks, weight and other details.

No fasting is needed for this test. You can eat and drink normally.

Your report is usually ready in 24-48 hrs after the sample reaches our lab. We send it on WhatsApp and email, and you can also download it from the Reports page.

Please call our team to confirm whether home sample collection is available for your location and test.

This test needs a blood sample. No special preparation needed.

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